SBIR/STTR Funding Opportunities

Find more funding opportunities and specific topic areas at

Department of Agriculture SBIR Request for Application

Dept. of Health and Human Services (HHS) 

Dept. of Defense (DoD) – All open topics

Dept. of Health and Human Services (HHS)

  • Advancing Validated Drug Targets for Substance Use Disorders: SBIR and STTR. Due 2/18/2022.

Targeted funding opportunities from HHS on specific topics with various upcoming due dates can be found here.

National Science Foundation (NSF) 

  • NSF SBIR and STTR Phase I. Project Pitches are always accepted. Remaining submission window close dates: 9/2/2021 and 12/2/2021.

SBA Awards 33 States to Provide Small Businesses SBIR/STTR Assistance 

The U.S. Small Business Administration issued 33 Federal and State Technology (FAST) Partnership Program awards this week for specialized training, mentoring, and technical assistance to improve outcomes in the SBIR/STTR programs. Recipients cover a wide geographic area, and include state and local economic development organizations, Small Business Technology Development Centers, Women’s Business Centers, Procurement Technical Assistance Centers, incubators, accelerators, colleges, and universities.  All organizations will provide support to small businesses developing advanced technologies and support underserved communities by increasing participation from women-owned, rural-based, and socially or economically disadvantaged small businesses. More information is available in the award announcement, and the full list of FAST awardees is at

Recordings from the 2021 National SBIR Week are Now Posted! 

Whether or not you were one of the more than 5,000 people who registered to attend National SBIR Week, presentations are now available to view. Learn how to start your SBIR application, hear from agency program managers on the most common and avoidable applicant mistakes, discover what agencies look for in transitioning from Phase I to Phase II and on to Phase III, and more! Recordings of the Minority Business Development Agency’s InVision tour, with SBIR awardee perspectives and how to partner with Federal labs or Minority Serving Institutions, are also now availableRead a summary of the week with resource links.

DOE Funding Opportunity Now Open, Apply to Phase 0 Application Assistance Program 

The Department of Energy’s (DOE) SBIR/STTR office released their Phase I funding opportunity on August 9 and still has space in their Phase 0 application assistance program. DOE’s Phase 0 program focuses on helping first-time SBIR/STTR applicants understand the proposal process and prepare competitive applications. More information is available here, and the agency’s current funding topics are available here.

SBIR/STTR Innovation Conference to be Held In-Person this October 

Join us on October 18 – 20, 2021 at the Gaylord at National Harbor, for the 2021 SBIR/STTR Innovation Conference. The event will convene past, current, and potential SBIR/STTR applicants, as well as researchers, small businesses, and agency officials. There will be opportunities to hear from past SBIR/ STTR awardees and agency SBIR/STTR program managers as they outline funding, strategies, and support for American innovation. The SBIR/ STTR Innovation Conference will run concurrently with the TechConnect World Innovation Conference and Expo. These exciting events provide opportunities to learn more about the SBIR/STTR programs and potentially connect with innovators across technology areas. More information about the SBIR/STTR conference is available here, and the full TechConnect program is available here.

Help is Available For Preparing a Responsive Proposal 

Interested in learning how to prepare a responsive proposal to solicitation guidelines? Check out the online tutorial available to help you understand the proposal evaluation criteria, develop a proposal preparation schedule, build a winning team, and more. Access the full tutorial on proposal preparation, and check out all the courses available to help you learn more about the Small Business Innovation Research (SBIR) and the Small Business Technology Transfer (STTR) programs at

Events & Education

TechConnect World Innovation Conference and Expo | Oct. 18 – 20, Washington, D.C. | Register

Look for upcoming events at

R&D Spotlight

Useful Stats: SBIR/STTR Application Success Rates Decreased from 2019 to 2020 at NASA 

An SSTI data analysis finds that in fiscal year (FY) 2020 small businesses were less successful in obtaining SBIR and STTR funding from NASA than they were in FY 2019. A helpful metric used by organizations dedicated to supporting technology startups and bolstering local innovation economies is the success rate of companies applying to the SBIR/STTR programs. Understanding how successful local companies are at submitting quality applications and winning SBIR/STTR awards can better assist in designing outreach, education, technical assistance, mentorship, and other entrepreneurial support programs. This edition of Useful Stats examines recently updated NASA data on the agency’s SBIR/STTR application success rates by state from 2019 to 2020.

USPTO Announces Deadline for Patents for Humanity COVID-19 Award 

September 30, 2021 at 5 p.m. ET is the final deadline for submitting an application to the United States Patent and Trademark Office (USPTO) for its Patents for Humanity COVID-19 award. Award winners will receive a certificate to accelerate USPTO processing for one eligible matter. This new award category was launched April 5, 2021, for patent applicants, holders, and licensees whose inventions track, prevent, diagnose, or treat COVID-19. The program highlights COVID-19 success stories that inspire others to harness innovation for human progress and any U.S. patent or patent application that addresses COVID-19 is eligible for this award. For details about how to apply, visit the USPTO’s Patents for Humanity COVID-19 page on the USPTO website.

Highlights for Ecosystem Builders

EDA Announces $3 billion in Funding for American Rescue Plan Programs 

The Economic Development Administration (EDA) announced $3 billion in funding for their American Rescue Plan programs. These programs are intended to help communities build back better following the coronavirus pandemic and prepare communities for future economic shocks. The EDA is administering this funding under six different programs with varying eligibility and application deadlines. For those interested in learning more about the programs or applying, visit EDA’s American Rescue Plan programs page.

EDA Announces STEM Talent Challenge 

The EDA announced the STEM Talent Challenge which will support programs to train talent and fuel STEM-focused regional economies. The challenge is funded at $2 million and applicants can request up to $250,000 to implement 24-month workforce programs. The deadline to apply is October 12, 2021 and EDA will host a webinar to provide more details regarding the application process. Updates can be found here.

Get inspired by more SBIR company stories at and learn about all the 2020 Tibbetts Award winners at

About America’s Seed Fund Update

Our goal is to provide a range of information that will be valuable to the SBIR/STTR programs’ various stakeholders, and future issues will include features on program data, impacts and policies, and more. If you have suggestions, let us know at

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About SBA Office of Innovation and Technology

The U.S. Small Business Administration serves as the coordinating agency for the Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs – also known as America’s Seed Fund. SBA also manages the related Federal and State Technology (FAST) Partnership Program and Growth Accelerator Fund Competition. Learn more at